Acxion AP, the weight‑loss medicine sold in Canada
uick overview:
- What it is: Brand of phentermine (a prescription stimulant anorectic). “AP” is a prolonged/extended‑release formulation.
- Indication: Short‑term adjunct (a few weeks) to diet, exercise, and behavioral changes for obesity when BMI is high or there are weight‑related conditions, under a clinician’s supervision.
- Common strengths: Often 30 mg ER once daily (formulations can vary by market).
- How it works: Increases norepinephrine (and to a lesser extent dopamine) to suppress appetite and reduce caloric intake.
Important safety info:
- Do not use if: You have cardiovascular disease, uncontrolled hypertension, hyperthyroidism, glaucoma, agitated states, history of drug misuse, or during pregnancy/breastfeeding. Contraindicated with MAO inhibitors (within 14 days).
- Warnings: Can raise blood pressure/heart rate; risk of insomnia, anxiety, dry mouth, constipation, headache, palpitations. Rare but serious: primary pulmonary hypertension, valvular heart disease, stroke, psychosis. Risk of dependence/tolerance.
- Interactions: MAOIs, other stimulants (ADHD meds, decongestants), certain antidepressants, alcohol, some antihypertensives. Caution with SSRIs/SNRIs due to additive effects (monitor BP, anxiety).
- Duration: Typically limited to short‑term use; longer use requires careful medical oversight.
- Legal/availability: Commonly prescribed in Mexico. In the U.S., phentermine is prescription‑only; importing foreign meds for personal use can be illegal and unsafe.
Tips for safer use (only under medical guidance):
- Take in the morning to avoid insomnia.
- Monitor blood pressure and heart rate.
- Avoid caffeine and other stimulants.
- Combine with a structured nutrition and activity plan.
- Stop and seek care for chest pain, fainting, severe shortness of breath, new edema, or mood/behavior changes.
Alternatives to discuss with your doctor:
- Non‑stimulants: Orlistat.
- Combination: Phentermine/topiramate ER.
- GLP‑1/dual agonists: Semaglutide, tirzepatide (effective for chronic weight management).
- Lifestyle/behavioral therapy and, where appropriate, bariatric procedures.
If you can share your goal (e.g., general info vs. dosing guidance, side effects you’re experiencing, interactions with a specific medication), I can tailor this to your situation. This is general information and not a substitute for medical advice.






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